Temporary Research Associate – Analytical & Purification

Vertex Pharmaceuticals Inc (US) Boston, MA

About the Job

The Analytical & Purification team within the Medicinal Chemistry Group is seeking an energetic, results-oriented individual with a passion for learning, strong communication and organizational skills as well as a sense of creativity and a mind for the technical. This individual will support the liquid chromatography purification platform within the medicinal chemistry group. The individual will propose and develop improvements in the purification workflow along with implementation of new methods and technologies for high throughput separations. In addition, the successful applicant will possess broad analytical chemistry skills and be able to contribute analytical chemistry solutions to challenges facing drug discovery teams.

Key Responsibilities
 

  • Purification of medicinal chemistry compounds in a high throughput automated environment
  • Developing and optimizing purification methods for specific compounds and classes of compounds
  • Operating and troubleshooting laboratory and open access instrumentation
  • Consulting with medicinal chemists to develop optimal solutions in accord with project goals
  • Understanding of the drug discovery and medicinal chemistry process
  • Analysis of complex mixtures and developing separation methods
  • Introduction of new methodologies in support of compound purifications and lab operations
  • Active participation in discussions in chemistry team meetings
  • Presentation of results to chemistry and project teams
     

Minimum Qualifications
 

  • Master’s or Bachelor’s Degree with 0-5+ years industrial experience in a relevant setting
     

Preferred Qualifications
 

  • Experience in chemical compound purification
  • Experience in automation and instrumentation
  • Strong background in informatics and automation, or a willingness to learn
  • Ability to multi-task and deliver on multiple projects and targets simultaneously
  • Advanced knowledge of operation of standard laboratory instrumentation (e.g. liquid handlers, MS, automated chromatography, SFC, chiral chromatography, etc.), as well as demonstrated capabilities in modern methods of synthesis and analysis
  • Positive attitude, customer-oriented focus and an attention to detail are critical to success in this position
  • Track record evidenced by a strong publication or patent record