Pharmacology Research Scientist I

Vertex Pharmaceuticals Inc (US) San Diego, CA

About the Job

Research scientist I with proven experience planning, executing, and analyzing complex and challenging in vitro, ex vivo, and in vivo pharmacology assays.  Ideal candidate will have experience in primary human cell and neuronal cell culture, live cell imaging platforms, in vivo pharmacology assays, ex vivo receptor occupancy, and tissue IHC & RNAscope/ISH.  The candidate is expected to be independent, well organized, productive, fearless, have a high level of knowledge in neuroscience, pharmacology or pain areas, and to be an effective communicator.

Minimum Qualifications:

  • PhD with 0-3 years postdoctoral experience or MS/BS with 3+/6+ years industry experience
  • Experience planning, executing, & analyzing in vitro and/or in vivo pharmacology studies
  • Human primary cell and/or rodent neuronal cell culture
  • Proficient in analyzing complex data sets and concisely disseminating results
  • Rodent handling proficiency

Preferred Qualifications

  • Experience with high content imaging, confocal, or other live-cell imaging platforms
  • Tissue IHC and in situ hybridization, and ex vivo receptor occupancy experience
  • Dosing, sampling, dissection, and behavioral pharmacology experience
  • Evidence for patent and/or literature publication
  • Strong background in neurobiology, electrophysiology, live cell imaging, and pain
  • Well organized, independent, effective communicator, fearless pursuit of excellence