Senior Scientist (Group Lead), Cell Culture Development

Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue of about $40 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies or increasing productivity in their laboratories, we are here to support them. Our global team of more than 100,000 colleagues delivers an unrivaled combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon and PPD.

Do you have a passion for innovative ideas and groundbreaking discoveries? With over $1 billion invested annually in R&D, at Thermo Fisher Scientific you’ll help tackle some of the world’s toughest challenges, from giving cancer patients hope, ensuring safe drinking water and helping law enforcement solve cases through forensics. We empower our teams to put science into meaningful action and give our R&D colleagues the autonomy, resources and tools they need to take science a step beyond.

Work Location: Princeton, NJ

• This position is ONLY available at the Princeton, NJ site *OPEN TO RELOCATION*

Group: Pharma Services Group
Division: Drug Substance
Business Unit: Biologics BPS

How will you make an impact?
Directly manages a team of upstream process development scientists. This position will be responsible for leading projects such as media/feed optimization, bioreactor process development and process characterization. Works on technical/scientific project activities to execute strategies and technical solutions that meet client needs and expectations. Leads technical discussions with clients with a high level of technical proficiency. Evaluates and oversees the design of processes and supports problem solving. Makes decisions that require developing new options to solve complex problems. Determines methods and procedures on new assignments and may coordinate activities of other employees.

What Will You Do?

• Act as a lead upstream scientist on multiple programs having project oversight and direct and indirect report management responsibilities.
• Plan project scope, timing and resource requirements.
• Design and develop mammalian cell culture processes to support the production and manufacturing of recombinant proteins (including mAbs) with activities including:
• Clone and media/feed screening using AMBR technology
• Bioreactor culture development including fed-batch, perfusion and XD® technologies (2 to 250L scale) with both glass and single use cell culture technologies.
• Design experimental plans based on the defined deliverables, planning the activities to meet the project timelines by working closely with project managers.
• Investigate, create, and validate new scientific methodologies on a complex scope of projects.
• Lead the transfer of developed upstream processes to the global manufacturing network including documentation and technical know-how.
• Author, review and approve process development reports and technology transfer protocols.
• Participate in project-team meetings. Present and discuss the data and project progress at those meetings.
• Stay current with relevant technologies and scientific literature.

• Bachelor's degree, Master's degree, or PhD in biology, chemistry, biochemistry, chemical engineering, or a related field.

• 4+ years of industry experience related to Biologics manufacturing, upstream process development, and process engineering
• Upstream bioprocessing experience utilizing mammalian cell cultures; experienced in designing and optimizing cell culture processes with manufacturing in mind.
• Demonstrated experience working with bioreactors.

• Strong knowledge of GMP regulations in cGMP manufacturing environment.
• Excellent problem solving and critical thinking skills.
• Excellent writing, communication and presentation skills.
• Strong MS Excel, PowerPoint and Word skills. Microsoft Project skills preferred.
• Excellent organization and planning skills.
• Strong attention to detail and ability to adhere to standards procedures.
• Drive functional, technical and operational excellence.
• Inspire and foster innovation, collaboration, transparency and team effectiveness.
• Design complex studies based on the deliverables.
• Analyze and summarize complex scientific data.
• Author reports, procedures, and other documents.
• Function in a rapidly changing environment.
• Read, analyze, and interpret general business periodicals, professional journals, technical procedures, or governmental regulations.
• Make and communicate complex decisions.
• Speak effectively before groups of customers and employees.
• Apply complex mathematical concepts to physical problems in areas such as heat and mass transport.

This position has been approved for relocation assistance.

Our global team of more than 100,000 colleagues delivers an unrivaled combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services and Patheon. For more information, please visit www.thermofisher.com.

Apply today! http://jobs.thermofisher.com

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.