Scientist I, Antibody Engineering

Astellas
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Job Details

  • Location: South San Francisco, CA, 94101
  • Date Posted: 2026-01-07
  • Employment Type: Full Time
  • Category: Chemists
  • Req Number: 25-POS00085258
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Description

Scientist I, Antibody Engineering

 

Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians.  If you want to be part of this exciting work, you belong at Astellas!

 

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at www.astellas.com.

 

Astellas is announcing a Scientist I, Antibody Engineering opportunity at the Xyphos affiliate at the Astellas West Coast Innovation and Research Center in South San Francisco, CA.

 

Purpose:

We are seeking a talented Scientist to join our Antibody Engineering team in South San Francisco. This role will contribute to the design, molecular biology, purification and characterization of next-generation biologics, with a focus on innovative platform technology development for oncology programs.

 

Essential Job Responsibilities:

  • Lead antibody and protein production by performing purification of mAbs, bi-/multi-specific antibodies, and Fc fusion proteins at various scales using CHO and 293 cell lines
  • Perform QC and characterize recombinant antibodies and proteins from both internal and external sources; summarize results and present to project teams
  • Act as a technical lead for maintaining priority work and troubleshooting production issues
  • Plan and coordinate internal and external production activities and communicate with key stakeholders regularly